report cover1

Chorea Associated with Huntington's Disease Market - Global Industry, Analysis, Size, Share, Growth, Trends, and Forecasts 2023-2030

Huntington’s disease is characterized by movement disorders, cognitive decline, and psychiatric symptoms. The most common presenting feature of Huntington’s disease is chorea. Choreic movements consist of involuntary, unpredictable, jerk-like muscle contractions that randomly involve different body parts and vary in frequency, intensity, and amplitude. Thus, choreic movements may range from very subtle twitches involving the eyebrows or other parts of the upper face to severe, generalized contractions involving the limbs and trunk interfering with the patient’s speech, swallowing, gate, balance, and other motor activities. Involvement of the upper face, manifested by intermittent irregular blinking or brief contractions of the orbital portion of the orbicularis oculi, procerus, and corrugator muscles helps differentiate chorea associated with Huntington’s disease from tardive dyskinesia, which only very rarely involves the upper face.

In addition to the involvement of the upper face, chorea also may affect the mouth and tongue, manifested by impersistence of tongue protrusion and dysarthria, commonly observed even early stage of Huntington’s disease. Choreic movements are continuous and present essentially constantly when the patient is awake, although some bed partners of patients report jerk-like movements at night while asleep. The intensity of chorea is influenced by emotions and other stress factors, such as fatigue, anxiety, and a variety of other psychological and socioeconomic stressors. In the early stages of the disease, chorea is either unnoticed or its presence is denied by the patients, who may consciously or subconsciously camouflage it by incorporating it into deliberate movements. Many patients are unaware of the Choreic movements and often minimize their severity. chorea minima is used to describe low-amplitude chorea, which occurs especially in children and adolescents.

Global Chorea Associated with Huntington’s Disease Market – Competitive Landscape

The companies actively engaged in research and development to introduce innovative therapeutic interventions for managing Chorea symptoms in Huntington’s disease. Market dynamics also include collaborations, mergers, and acquisitions contributing to strategic advancements in treatment options. Ongoing clinical trials and regulatory approval shape the evolving landscape, with a focus on improving patient outcomes and addressing unmet medical needs in these challenging neurodegenerative disorders.

Some of the Key Players in the Global Chorea Associated with Huntington’s Disease Market Include –

  • Pfizer
  • Alnylam Pharmaceutical Inc.
  • Teva Pharmaceutical Industries Inc.
  • Neurocrine Bioscience Inc.
  • Novartis AG
  • UniQure
  • Prilenia Therapeutics
  • SOM Biotech
  • Bausch Health Companies

Global Chorea Associated with Huntington’s Disease Market – Growth Drivers

The rising incidence of Huntington’s disease worldwide serves as a primary growth driver, creating a larger patient population in need of effective treatments for Chorea symptoms. According to Rare Diseases Advisor Huntington’s disease prevalence ranges from 3 to 7 per 100,000 persons among those with European ancestry. The prevalence in Europe is estimated at 6.37 per 100,000 persons, and in North America, 8.87 per 100,000 persons. Ongoing research efforts and advancement in understanding the molecular and genetic basis of Huntington’s disease contribute to the development of targeted therapies, driving market growth. The global increase in the elderly population, who are more susceptible to neurodegenerative diseases like Huntington’s is a significant growth driver for the Chorea associated with Huntington’s disease market. Continued technological innovations in therapeutic approaches, including gene therapies and neuroprotective agents, drive growth by offering new and more effective treatment options. Incentives and investments in orphan drug development create opportunities for pharmaceutical companies to focus on niche markets, including Chorea associated with Huntington’s disease, driving overall market growth. Increasing awareness about Huntington’s disease and its associated Chorea symptoms among healthcare professionals and the general public drives early diagnosis and intervention, supporting market growth. Government support through funding and regulatory incentives for research and development activities related to Huntington’s disease contributes significantly to market growth. Improved access to healthcare services globally, especially in developing regions, enhances the diagnosis and management of Huntington’s disease, fostering market growth. The presence of a robust pipeline of promising therapies in various stages of development fuels optimism and contributes to the overall growth of the Chorea associated with Huntington’s disease market.

Global Chorea Associated with Huntington’s Disease Market – Restraints

The scarcity of approved and effective treatments for Chorea associated with Huntington’s disease acts as a significant restraint, limiting the available therapeutic interventions. The substantial cost associated with research, development, and clinical trials of potential treatments poses a financial challenge for companies, potentially hindering the pace of new therapeutic discoveries. According to Science Direct Huntington’s disease costs in early stages increased up to USD 22,582. The complex and multifaceted nature of Huntington’s disease poses challenges in understanding its pathology, making it difficult to develop targeted and curative treatments for Chorea symptoms. The absence of disease-modifying therapies that can alter the course of Huntington’s disease progression presents a significant restraint, as current treatments mainly focus on symptom management. Ethical considerations related to genetic testing, coupled with regulatory challenges, may hinder the development and adoption of certain therapies, impacting the overall market landscape. Low levels of awareness about Huntington’s disease and challenges in early diagnosis contribute to delayed treatment initiation, affecting the overall market potential. The stigma and psychological impact associated with genetic testing for Huntington’s disease can discourage individuals from undergoing testing, leading to delayed diagnosis and treatment. The genetic variability observed in individuals with Huntington’s disease treatments may create financial barriers for patients impacting the market adoption of available therapies. The lengthy development timelines associated with bringing new therapies to market can slow down the availability of innovative treatments for chorea associated with Huntington’s disease.

Global Chorea Associated with Huntington’s Disease Market – Opportunities

Opportunities lie in the continuous research and development of innovative therapies targeting Chorea associated with Huntington’s disease, providing avenues for novel treatment modalities. Conducting extensive global clinical trials creates opportunities to gather diverse data, ensuring a comprehensive understanding of treatment efficacy and safety across different populations. The integration of telemedicine and remote monitoring technologies presents opportunities to enhance patient care, especially for those in remote areas, by providing regular follow-ups and monitoring of symptoms. Investment in biomarker research allows for the identification of reliable indicators, aiding in early diagnosis, disease monitoring, and assessment of treatment efficacy.

Global Chorea Associated with Huntington’s Disease Market – Geographical Insight

The market for global chorea associated with Huntington’s disease is segmented into regions such as North America, Latin America, Europe, Asia-Pacific, the Middle East & Africa. North America is the largest market for global chorea associated with Huntington’s disease due to the high prevalence of Huntington’s disease in the United States and Canada contributes to the market’s prominence in this region. Europe is a key market for Chorea associated with Huntington’s disease, with several pharmaceutical companies actively participating in research and development efforts. The region benefits from robust healthcare infrastructure and a relatively higher awareness of neurological disorders.

Global Chorea Associated with Huntington’s Disease Market – Key Development

  • On August 18, 2023, Neurocrine Biosciences announced FDA approval of INGREZZA® capsules for the treatment of Chorea associated with Huntington’s disease.
  • On February 18, 2023, Teva announced FDA approval of Austedo® XR extended-release tablets, a new once-daily formulation for Chorea associated with Huntington’s disease.
Complete the form below and we'll get back to you shortly
Table of Content
Complete the form below and we'll get back to you shortly

Research Methodology: Aspects

Market research is a crucial tool for organizations aiming to navigate the dynamic landscape of customer preferences, business trends, and competitive landscapes. At Cognizance Market Research, acknowledging the importance of robust research methodologies is vital to delivering actionable insights to our clientele. The significance of such methodologies lies in their capability to offer clarity in complexity, guiding strategic management with realistic evidence rather than speculation. Our clientele seek insights that excel superficial observations, reaching deep into the details of consumer behaviours, market dynamics, and evolving opportunities. These insights serve as the basis upon which businesses craft tailored approaches, optimize product offerings, and gain a competitive edge in an ever-growing marketplace.

The frequency of information updates is a cornerstone of our commitment to providing timely, relevant, and accurate insights. Cognizance Market Research adheres to a rigorous schedule of data collection, analysis, and distribution to ensure that our reports reflect the most current market realities. This proactive approach enables our clients to stay ahead of the curve, capitalize on emerging trends, and mitigate risks associated with outdated information.

Our research process is characterized by meticulous attention to detail and methodological rigor. It begins with a comprehensive understanding of client objectives, industry dynamics, and research scope. Leveraging a combination of primary and secondary research methodologies, we gather data from diverse sources including surveys, interviews, industry reports, and proprietary databases. Rigorous data analysis techniques are then employed to derive meaningful insights, identify patterns, and uncover actionable recommendations. Throughout the process, we remain vigilant in upholding the highest standards of data integrity, ensuring that our findings are robust, reliable, and actionable.

Key phases involved in in our research process are mentioned below:


Understanding Clients’ Objectives:

Extensive Discussions and Consultations:

  • We initiate in-depth discussions and consultations with our clients to gain a comprehensive understanding of their objectives. This involves actively listening to their needs, concerns, and aspirations regarding the research project.
  • Through these interactions, we aim to uncover the underlying motivations driving their research requirements and the specific outcomes they hope to achieve.

Industry and Market Segment Analysis:

  • We invest time and effort in comprehensively understanding our clients’ industry and market segment. This involves conducting thorough research into market trends, competitive dynamics, regulatory frameworks, and emerging opportunities or threats.
  • By acquiring a deep understanding of the broader industry landscape, we can provide context-rich insights that resonate with our clients’ strategic objectives.

Target Audience Understanding:

  • We analyze our clients’ target audience demographics, behaviors, preferences, and needs to align our research efforts with their consumer-centric objectives. This entails segmenting the audience based on various criteria such as age, gender, income level, geographic location, and psychographic factors.
  • By understanding the nuances of the target audience, we can tailor our research methodologies to gather relevant data that illuminates consumer perceptions, attitudes, and purchase intent.


Identifying Challenges and Opportunities:

  • We proactively identify the challenges and opportunities facing our clients within their respective industries. This involves conducting SWOT (Strengths, Weaknesses, Opportunities, Threats) analyses and competitive benchmarking exercises.
  • By identifying potential obstacles and growth drivers, we can provide strategic recommendations that help our clients navigate complexities and capitalize on emerging opportunities effectively.

Grasping Specific Goals:

  • We delve into the intricacies of our clients’ objectives to gain clarity on the specific goals they aim to accomplish through the research. This entails understanding their desired outcomes, such as market expansion, product development, or competitive analysis.
  • By gaining a nuanced understanding of our clients’ goals, we can tailor our research approach to address their unique challenges and opportunities effectively.

Data Collection:


Primary Research Process:

  • Surveys: We design and administer surveys tailored to capture specific information relevant to our clients’ objectives. This may involve employing various survey methodologies, such as online, telephone, or face-to-face interviews, to reach target audiences effectively.
  • Interviews: We conduct structured or semi-structured interviews with key stakeholders, industry experts, or target consumers to gather in-depth insights and perspectives on relevant topics. These interviews allow us to probe deeper into specific issues and uncover valuable qualitative data.
  • Focus Groups: We organize focus group discussions with carefully selected participants to facilitate interactive discussions and gather collective opinions, attitudes, and preferences. This qualitative research method provides rich contextual insights into consumer behaviors and perceptions.
  • Observations: We conduct observational research by directly observing consumer behaviors, interactions, and experiences in real-world settings. This method enables us to gather objective data on consumer actions and reactions without relying on self-reported information.

Secondary Research Process:

  • Literature Review: We conduct comprehensive literature reviews to identify existing studies, academic articles, and industry reports relevant to the research topic. This helps us gain insights into previous research findings, theoretical frameworks, and best practices.
  • Industry Reports: We analyze industry reports published by reputable trade associations (whitepapers, research studies, etc.), and government agencies (U.S. Census Bureau, Bureau of Labor Statistics, and Securities and Exchange Commission etc.) to obtain macro-level insights into market trends, competitive landscapes, and industry dynamics.
  • Government Publications: We review government publications, such as economic reports, regulatory documents, and statistical databases, to gather relevant data on demographics, market size, consumer spending patterns, and regulatory frameworks.
  • Online Databases: We leverage online databases, such as industry portals, and academic repositories (PubMed Central (PMC), ScienceDirect, SSRN (Social Science Research Network), Directory of Open Access Journals (DOAJ), NCBI, etc.), to access a wide range of secondary data sources, including market statistics, financial data, and industry analyses.



Data Analysis:

The data analysis phase serves as a critical juncture where raw data is transformed into actionable insights that inform strategic decision-making. Through the utilization of analytical methods such as statistical analysis and qualitative techniques like thematic coding, we uncover patterns, correlations, and trends within the data. By ensuring the integrity and validity of our findings, we strive to provide clients with accurate and reliable insights that accurately reflect the realities of the market landscape.


Transformation of Raw Data:

  • Upon collecting the necessary data, we transition into the data analysis phase, where raw data is processed and transformed into actionable insights. This involves organizing, cleaning, and structuring the data to prepare it for analysis.

Utilization of Analytical Methods:

  • Depending on the research objectives, we employ a diverse range of analytical methods to extract meaningful insights from the data. These methods include statistical analysis, trend analysis, regression analysis, and qualitative coding.

Statistical Analysis:

  • Statistical tools are instrumental in uncovering patterns, correlations, and trends within the data. By applying statistical techniques such as descriptive statistics, hypothesis testing, and multivariate analysis, we can discern relationships and derive valuable insights.

Qualitative Analysis Techniques:

  • In addition to quantitative analysis, we leverage qualitative analysis techniques to gain deeper insights from qualitative data sources such as interviews or open-ended survey responses. One such technique is thematic coding, which involves systematically categorizing and interpreting themes or patterns within qualitative data.

Integrity and Validity Maintenance:

  • Throughout the analysis process, we maintain a steadfast commitment to upholding the integrity and validity of our findings. This entails rigorous adherence to established methodologies, transparency in data handling, and thorough validation of analytical outcomes.

Data Validation:

The final phase of our research methodology is data validation, which is essential for ensuring the reliability and credibility of our findings. Validation involves scrutinizing the collected data to identify any inconsistencies, errors, or biases that may have crept in during the research process. We employ various validation techniques, including cross-referencing data from multiple sources, conducting validity checks on survey instruments, and seeking feedback from independent experts or peer reviewers. Additionally, we leverage internal quality assurance protocols to verify the accuracy and integrity of our analysis. By subjecting our findings to rigorous validation procedures, we instill confidence in our clients that the insights they receive are robust, reliable, and trustworthy.


Importance of Data Validation:

  • Data validation is the final phase of the research methodology, crucial for ensuring the reliability and credibility of the findings. It involves a systematic process of reviewing and verifying the collected data to detect any inconsistencies, errors, or biases.

Scrutiny of Collected Data:

  • The validation process begins with a thorough scrutiny of the collected data to identify any discrepancies or anomalies. This entails comparing data points, checking for outliers, and verifying the accuracy of data entries against the original sources.

Validation Techniques:

  • Various validation techniques are employed to ensure the accuracy and integrity of the data. These include cross-referencing data from multiple sources to corroborate findings, conducting validity checks on survey instruments to assess the reliability of responses, and seeking feedback from independent experts or peer reviewers to validate the interpretation of results.

Internal Quality Assurance Protocols:

  • In addition to external validation measures, internal quality assurance protocols are implemented to further validate the accuracy of the analysis. This may involve conducting internal audits, peer reviews, or data validation checks to ensure that the research process adheres to established standards and guidelines.
- Get Started -

Get insights that lead to new growth opportunities

Need a Custom Report?

We can customize every report – free of charge – including purchasing stand-alone sections or country-level reports

Want to Buy a Report but have a Limited Budget?

We help clients to procure the report or sections of the report at their budgeted price. Kindly click on the below to avail

Business Development

small c popup.png
Buy Now
small c popup.png
Complete the form below and we'll get back to you shortly
small c popup.png
Complete the form below and we'll get back to you shortly
small c popup.png
Complete the form below and we'll get back to you shortly
Ask an Expert