report cover1

Bivalent Norovirus Market - Global Industry, Analysis, Size, Share, Growth, Trends, and Forecasts 2023-2030

Bivalent norovirus refers to a strain of the norovirus, a highly contagious and commonly encountered virus responsible for causing acute gastroenteritis in humans. Norovirus are characterized by their genetic diversity, with several genogroups and genotypes identified. The term bivalent specifically indicates a strain that possesses a dual classification or reactivity to two different types within the norovirus classification system. This classification system is based on the genetic makeup of the virus, particularly the sequences of its major capsid protein. Norovirus is notorious for causing outbreaks of gastroenteritis in various settings, including cruise ships, schools, and healthcare facilities. Symptoms typically include sudden onset of vomiting, diarrhea, nausea, and stomach cramps. The ability of norovirus to rapidly spread in crowded or enclosed environments makes it a significant public health concern. Bivalent norovirus, with its dual reactivity, suggests a genetic makeup that shares characteristics with two distinct types within the norovirus classification. Norovirus belongs to the Caliciviridae family and is classified into different genogroups (I, II, III) each further divided into genotypes based on genetic diversity, particularly in the major capsid protein. This genetic variation may contribute to the virus’s ability to adapt and evade immunity, posing challenges for vaccine development and control strategies.

The major capsid protein, encoded by the VP1 gene, plays a crucial role in the virus’s ability to infect and interact with host cells. Variability in this protein contributes to the diverse strains and genotypes observed within the norovirus population. Understanding the genetic diversity of norovirus is essential for several reasons. Firstly, it influences the virus’s ability to escape host immunity, making it challenging to develop a universal vaccine. Secondly, different norovirus strains may exhibit variations in transmission dynamics environmental stability, and clinical outcomes. Ongoing research in virology aims to uncover the specific genetic traits and mechanisms associated with bivalent norovirus strains.

Global Bivalent Norovirus Market – Competitive Landscape

On September 8, 2021, Norovirus vaccine developer Hillevax secured a USD 135 million crossover round. Investment significantly in research and development to address the growing demand for norovirus prevention. Many players are forming strategic alliances and collaborations with research institutions and governmental organizations to leverage collective expertise and resources in advancing bivalent norovirus vaccine development. Companies employ diverse commercialization strategies, including marketing campaigns, pricing models, and distribution networks. Successful commercialization requires a comprehensive understanding of market needs and effective communication of vaccine benefits.

Some of the Key Players in the Global Bivalent Norovirus Market Include –

  • Merck
  • GSK
  • Sanofi
  • Vaxart
  • AstraZeneca
  • Bavarian Nordic
  • Mitsubishi Tanbe Pharma Corporation

Global Bivalent Norovirus Market – Growth Drivers

The rising prevalence of norovirus infections globally creates a strong demand for effective preventive measures, driving growth in the bivalent norovirus vaccine market. According to Biomed Central, the prevalence rate of norovirus in different age groups ranged from 8.3% to 22.4%. the global focus on preventive healthcare, especially in the context of infectious diseases, contributes to the growth of the bivalent norovirus market as vaccines become integral components of public health strategies. Ongoing efforts to enhance pandemic preparedness worldwide drive investments in infectious disease prevention, positioning bivalent norovirus vaccines as essential tools in mitigating future outbreaks. Continuous advancements in vaccine technologies, including novel delivery systems and adjuvants, accelerate the development of more efficacious and practical bivalent norovirus vaccines. The inclusion of bivalent norovirus vaccines in global vaccination campaigns and immunization programs enhances accessibility and contributes to market growth, especially in regions with high norovirus prevalence. Increasing awareness through public health campaigns about the impact of norovirus infections and the availability of preventive vaccines stimulates demand and fosters market growth. Collaboration between research institutions, pharmaceutical companies, and international organizations accelerates the pace of bivalent norovirus vaccine development, fostering innovation and market growth. Increasing healthcare expenditure globally, particularly in infectious disease prevention, provides a conducive environment for investments in research, development, and commercialization of bivalent norovirus vaccines.

Global Bivalent Norovirus Market – Restraints

The diverse and evolving nature of norovirus strains poses a challenge in developing bivalent vaccines that effectively cover the wide range of circulating variants. An incomplete understanding of norovirus immunity and the lack of a correlate of protection complicate the development and evaluation of bivalent norovirus vaccines. Vaccine development for norovirus faces technical challenges, including the absence of robust animal models and difficulties in replicating human norovirus in vitro. The complex structure of norovirus and challenges in large-scale production may hinder the efficient and cost-effective manufacturing of bivalent norovirus vaccines. According to the National Center for Biotechnology Information (NCBI), the norovirus vaccine cost per child approximately USD 200. Economic disparities among countries can limit the widespread adoption of bivalent norovirus vaccines, especially in regions with limited financial resources. Variances in regulatory requirements across different regions create challenges for timely approvals and market entry, potentially delaying the availability of bivalent vaccines. Public perceptions, misinformation, and vaccine hesitancy may impede the acceptance and uptake of bivalent norovirus vaccines, affecting overall market success. Norovirus infections often result in short-lived immunity, raising concerns about the duration of protection offered by bivalent vaccines and the need for booster doses. The requirement for cold chain storage and distribution logistics poses challenges, especially in regions with limited infrastructure, potentially hindering vaccine accessibility. The lengthy and resource-intensive process of vaccine development, including clinical trials, may delay the availability of bivalent norovirus vaccines in the market.

Global Bivalent Norovirus Market – Opportunities

The global bivalent norovirus market has the potential to address an unmet medical need, providing a preventive solution for highly contagious and common gastrointestinal viruses. Increasing awareness of norovirus infections and their impact on public health creates a growing demand for bivalent vaccines presenting opportunities for bivalent norovirus market expansion. The ongoing focus on pandemic preparedness worldwide enhances the market’s potential, as bivalent norovirus vaccines contribute to preventive measures and reduce the burden on healthcare systems. Changes in norovirus epidemiology, including emerging strains or altered patterns, create opportunities for the adaptation of bivalent vaccines to effectively cover a broader spectrum of the virus.

Global Bivalent Norovirus Market – Geographical Insight

The market for global bivalent norovirus is segmented into regions such as North America, Latin America, Europe, Asia-Pacific, the Middle East & Africa. North America is the largest market for bivalent norovirus due to this region serves as a hub for clinical trials, contributing to the advancement of bivalent norovirus vaccine through rigorous testing and evaluation. Europe influences the approval process, ensuring that vaccines meet high safety and efficacy standards. The Asia-Pacific region sees the emergence of biotech firms and pharmaceutical companies entering the bivalent norovirus market, contributing to the global landscape. Diversity in patient populations across Asia-Pacific nations offers valuable insights during clinical trials, enhancing the understanding of vaccine efficacy.

Global Bivalent Norovirus Market – Key Development

  • On July 7, 2023, Positive topline data from the phase II trial of Vaxart’s norovirus vaccine pill.
  • On February 15, 2023, Vaxart doses the first subject in a bivalent norovirus vaccine trial.
Complete the form below and we'll get back to you shortly
Table of Content
Complete the form below and we'll get back to you shortly

Research Methodology: Aspects

Market research is a crucial tool for organizations aiming to navigate the dynamic landscape of customer preferences, business trends, and competitive landscapes. At Cognizance Market Research, acknowledging the importance of robust research methodologies is vital to delivering actionable insights to our clientele. The significance of such methodologies lies in their capability to offer clarity in complexity, guiding strategic management with realistic evidence rather than speculation. Our clientele seek insights that excel superficial observations, reaching deep into the details of consumer behaviours, market dynamics, and evolving opportunities. These insights serve as the basis upon which businesses craft tailored approaches, optimize product offerings, and gain a competitive edge in an ever-growing marketplace.

The frequency of information updates is a cornerstone of our commitment to providing timely, relevant, and accurate insights. Cognizance Market Research adheres to a rigorous schedule of data collection, analysis, and distribution to ensure that our reports reflect the most current market realities. This proactive approach enables our clients to stay ahead of the curve, capitalize on emerging trends, and mitigate risks associated with outdated information.

Our research process is characterized by meticulous attention to detail and methodological rigor. It begins with a comprehensive understanding of client objectives, industry dynamics, and research scope. Leveraging a combination of primary and secondary research methodologies, we gather data from diverse sources including surveys, interviews, industry reports, and proprietary databases. Rigorous data analysis techniques are then employed to derive meaningful insights, identify patterns, and uncover actionable recommendations. Throughout the process, we remain vigilant in upholding the highest standards of data integrity, ensuring that our findings are robust, reliable, and actionable.

Key phases involved in in our research process are mentioned below:


Understanding Clients’ Objectives:

Extensive Discussions and Consultations:

  • We initiate in-depth discussions and consultations with our clients to gain a comprehensive understanding of their objectives. This involves actively listening to their needs, concerns, and aspirations regarding the research project.
  • Through these interactions, we aim to uncover the underlying motivations driving their research requirements and the specific outcomes they hope to achieve.

Industry and Market Segment Analysis:

  • We invest time and effort in comprehensively understanding our clients’ industry and market segment. This involves conducting thorough research into market trends, competitive dynamics, regulatory frameworks, and emerging opportunities or threats.
  • By acquiring a deep understanding of the broader industry landscape, we can provide context-rich insights that resonate with our clients’ strategic objectives.

Target Audience Understanding:

  • We analyze our clients’ target audience demographics, behaviors, preferences, and needs to align our research efforts with their consumer-centric objectives. This entails segmenting the audience based on various criteria such as age, gender, income level, geographic location, and psychographic factors.
  • By understanding the nuances of the target audience, we can tailor our research methodologies to gather relevant data that illuminates consumer perceptions, attitudes, and purchase intent.


Identifying Challenges and Opportunities:

  • We proactively identify the challenges and opportunities facing our clients within their respective industries. This involves conducting SWOT (Strengths, Weaknesses, Opportunities, Threats) analyses and competitive benchmarking exercises.
  • By identifying potential obstacles and growth drivers, we can provide strategic recommendations that help our clients navigate complexities and capitalize on emerging opportunities effectively.

Grasping Specific Goals:

  • We delve into the intricacies of our clients’ objectives to gain clarity on the specific goals they aim to accomplish through the research. This entails understanding their desired outcomes, such as market expansion, product development, or competitive analysis.
  • By gaining a nuanced understanding of our clients’ goals, we can tailor our research approach to address their unique challenges and opportunities effectively.

Data Collection:


Primary Research Process:

  • Surveys: We design and administer surveys tailored to capture specific information relevant to our clients’ objectives. This may involve employing various survey methodologies, such as online, telephone, or face-to-face interviews, to reach target audiences effectively.
  • Interviews: We conduct structured or semi-structured interviews with key stakeholders, industry experts, or target consumers to gather in-depth insights and perspectives on relevant topics. These interviews allow us to probe deeper into specific issues and uncover valuable qualitative data.
  • Focus Groups: We organize focus group discussions with carefully selected participants to facilitate interactive discussions and gather collective opinions, attitudes, and preferences. This qualitative research method provides rich contextual insights into consumer behaviors and perceptions.
  • Observations: We conduct observational research by directly observing consumer behaviors, interactions, and experiences in real-world settings. This method enables us to gather objective data on consumer actions and reactions without relying on self-reported information.

Secondary Research Process:

  • Literature Review: We conduct comprehensive literature reviews to identify existing studies, academic articles, and industry reports relevant to the research topic. This helps us gain insights into previous research findings, theoretical frameworks, and best practices.
  • Industry Reports: We analyze industry reports published by reputable trade associations (whitepapers, research studies, etc.), and government agencies (U.S. Census Bureau, Bureau of Labor Statistics, and Securities and Exchange Commission etc.) to obtain macro-level insights into market trends, competitive landscapes, and industry dynamics.
  • Government Publications: We review government publications, such as economic reports, regulatory documents, and statistical databases, to gather relevant data on demographics, market size, consumer spending patterns, and regulatory frameworks.
  • Online Databases: We leverage online databases, such as industry portals, and academic repositories (PubMed Central (PMC), ScienceDirect, SSRN (Social Science Research Network), Directory of Open Access Journals (DOAJ), NCBI, etc.), to access a wide range of secondary data sources, including market statistics, financial data, and industry analyses.



Data Analysis:

The data analysis phase serves as a critical juncture where raw data is transformed into actionable insights that inform strategic decision-making. Through the utilization of analytical methods such as statistical analysis and qualitative techniques like thematic coding, we uncover patterns, correlations, and trends within the data. By ensuring the integrity and validity of our findings, we strive to provide clients with accurate and reliable insights that accurately reflect the realities of the market landscape.


Transformation of Raw Data:

  • Upon collecting the necessary data, we transition into the data analysis phase, where raw data is processed and transformed into actionable insights. This involves organizing, cleaning, and structuring the data to prepare it for analysis.

Utilization of Analytical Methods:

  • Depending on the research objectives, we employ a diverse range of analytical methods to extract meaningful insights from the data. These methods include statistical analysis, trend analysis, regression analysis, and qualitative coding.

Statistical Analysis:

  • Statistical tools are instrumental in uncovering patterns, correlations, and trends within the data. By applying statistical techniques such as descriptive statistics, hypothesis testing, and multivariate analysis, we can discern relationships and derive valuable insights.

Qualitative Analysis Techniques:

  • In addition to quantitative analysis, we leverage qualitative analysis techniques to gain deeper insights from qualitative data sources such as interviews or open-ended survey responses. One such technique is thematic coding, which involves systematically categorizing and interpreting themes or patterns within qualitative data.

Integrity and Validity Maintenance:

  • Throughout the analysis process, we maintain a steadfast commitment to upholding the integrity and validity of our findings. This entails rigorous adherence to established methodologies, transparency in data handling, and thorough validation of analytical outcomes.

Data Validation:

The final phase of our research methodology is data validation, which is essential for ensuring the reliability and credibility of our findings. Validation involves scrutinizing the collected data to identify any inconsistencies, errors, or biases that may have crept in during the research process. We employ various validation techniques, including cross-referencing data from multiple sources, conducting validity checks on survey instruments, and seeking feedback from independent experts or peer reviewers. Additionally, we leverage internal quality assurance protocols to verify the accuracy and integrity of our analysis. By subjecting our findings to rigorous validation procedures, we instill confidence in our clients that the insights they receive are robust, reliable, and trustworthy.


Importance of Data Validation:

  • Data validation is the final phase of the research methodology, crucial for ensuring the reliability and credibility of the findings. It involves a systematic process of reviewing and verifying the collected data to detect any inconsistencies, errors, or biases.

Scrutiny of Collected Data:

  • The validation process begins with a thorough scrutiny of the collected data to identify any discrepancies or anomalies. This entails comparing data points, checking for outliers, and verifying the accuracy of data entries against the original sources.

Validation Techniques:

  • Various validation techniques are employed to ensure the accuracy and integrity of the data. These include cross-referencing data from multiple sources to corroborate findings, conducting validity checks on survey instruments to assess the reliability of responses, and seeking feedback from independent experts or peer reviewers to validate the interpretation of results.

Internal Quality Assurance Protocols:

  • In addition to external validation measures, internal quality assurance protocols are implemented to further validate the accuracy of the analysis. This may involve conducting internal audits, peer reviews, or data validation checks to ensure that the research process adheres to established standards and guidelines.
- Get Started -

Get insights that lead to new growth opportunities

Need a Custom Report?

We can customize every report – free of charge – including purchasing stand-alone sections or country-level reports

Want to Buy a Report but have a Limited Budget?

We help clients to procure the report or sections of the report at their budgeted price. Kindly click on the below to avail

Business Development

small c popup.png
Buy Now
small c popup.png
Complete the form below and we'll get back to you shortly
small c popup.png
Complete the form below and we'll get back to you shortly
small c popup.png
Complete the form below and we'll get back to you shortly
Ask an Expert