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Advanced Metastatic Pancreatic Cancer Market - Global Industry, Analysis, Size, Share, Growth, Trends, and Forecasts 2023-2030

Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass. These cancerous cells can invade other parts of the body. Pancreatic cancer is the seventh leading cause of cancer-associated mortality worldwide. pancreatic cancer is hyper-aggressive and evolves from non-invasive precursor lesions. Therefore, only minor symptoms may be noticed in the early stage. The lack of specific risk factors makes early detection a formidable challenge. The tumor grows along with genetic and epigenetic alterations. Delays in diagnosis lead to poor prognosis. Advanced pancreatic cancer is when it is not removed by surgery. Most pancreatic cancer patients are diagnosed with advanced cancer. Metastatic pancreatic cancer is defined as stage IV cancer and it is not possible to completely remove it by surgery. Metastatic cancer is when the disease has spread to another area of the body. Pancreatic cancer often spreads to the liver, abdominal wall, lungs, bones, or faraway lymph nodes. Advanced metastatic pancreatic cancer is a cancer that spreads overall in the body and which is not removed by surgery. Pancreatic cancer may have some unexplained symptoms such as pain usually abdomen or back, weight loss, jaundice, loss of appetite, nausea, change in stool, and recent-onset diabetes. Advanced pancreatic cancer can be found by computed tomography scans, MRIs, and PETs.

Today, there is no established way or tool to find pancreatic cancer early. when diagnosed early, surgery offers the best chance of controlling pancreatic cancer for a long time. Most patients are diagnosed at later stages and are not eligible for surgery, though. So, tests to find pancreatic cancer in the earlier stages are urgently needed. Pancreatic cancer patients who participate in clinical research have better outcomes. Every treatment available today was approved through a clinical trial. The pancreatic cancer action network strongly recommends clinical trials at diagnosis and during every treatment decision.

Global Advanced Metastatic Pancreatic Cancer Market– Competitive Landscape

On September 26, 2023, PanCAN continued to accelerate new treatment options for patients with pancreatic cancer through the announcement of a USD 5 million grant to a biotechnology company at the leading edge of drug development. In October 2023, new cancer–focused venture capital firm debuted with USD 200 million in funding from prominent individuals and institutions such as MIT, Memorial Sloan Kettering Cancer Center, and Rockefeller University. On August 22, 2022, PanTher Therapeutics a clinical-stage oncology company developing next-generation targeted therapies for solid tumors, received a USD 14.2 million grant from the Cancer Prevention and Research Institute of Texas.

Some of the Key Players in the Global Advanced Metastatic Pancreatic Cancer Market Include

  • Pfizer Inc.
  • Hoffmann-La Roche Ltd.
  • AstraZeneca
  • Teva Pharmaceutical Industries Ltd.
  • Bayer AG
  • Amgen Inc.
  • Astellas Pharma Inc.
  • Novartis AG
  • Eli Lilly
  • Bristol Myers Squibb

Global Advanced Metastatic Pancreatic Cancer Market – Growth Drivers

The increasing prevalence rate of global advanced metastatic pancreatic cancer is increasing nowadays. According to the National Center for Biotechnology Information (NCBI), geographic distribution was observed more common in men 5.5% per 100,000, 243,033 cases, and in women 4.0 % per 100,000, 215,885 cases. The global aging population is at risk for cancer, including pancreatic cancer. As the population ages, there is a growing pool of potential patients. Improvements in diagnostic techniques enable earlier detection of pancreatic cancer, which can lead to better outcomes and increased demand for pancreatic cancer treatments. Increased awareness about pancreatic cancer and the implementation of screening programs in some regions can lead to earlier diagnoses, contributing to global advanced metastatic pancreatic cancer market growth. As healthcare infrastructure improves in developing countries, access to advanced cancer treatments becomes more widespread, increasing the market’s potential. Participation in clinical trials for novel cancer treatments provides patients with access to cutting-edge therapies and supports advanced metastatic pancreatic cancer market growth.

Global Advanced Metastatic Pancreatic Cancer Market – Restraints

Pancreatic cancer has historically had limited treatment options, and the development of effective therapies remains challenging, which can restrict advanced metastatic pancreatic cancer market growth. The cost of advanced cancer treatments can be prohibitively expensive, limiting access for some patients and posing a financial burden on healthcare systems. According to the National Center for Biotechnology Information (NCBI) mean total cost for patients with resectable locoregional disease is USD 134,700 and for those with unresectable locoregional or distant disease USD 65,300 and USD 49,000 respectively. Pancreatic cancer often presents at advanced stages, resulting in low survival rates, which can reduce the overall demand for advanced treatments. Many cancer treatments, including chemotherapy, can have severe side effects, which may deter some patients from pursuing treatment or adhering to therapies. The development of drug resistance in cancer patients can limit the long-term effectiveness of treatments, reducing their overall impact. Other types of cancer may receive more attention and research funding, diverting resources away from advanced metastatic pancreatic cancer research. Stringent regulatory requirements and lengthy approval processes for new cancer drugs can impede their timely entry into the global advanced metastatic pancreatic cancer market.

Global Advanced Metastatic Pancreatic Cancer Market – Opportunities

The development of immunotherapies such as checkpoint inhibitors and CART-T cell therapies, presents a significant opportunity for more effective and targeted treatment of pancreatic cancer. Advancements in genomics and personalized medicine offer opportunities to tailor treatments to the genetic profiles of individual patients potentially improving therapeutic outcomes. Identifying new biomarkers for early detection and prognosis can create opportunities for the development of innovative diagnostic and treatment approaches. Increasing healthcare spending worldwide provides a potential boost to the market, as it may lead to improved infrastructure and access to advanced cancer treatments.

Global Advanced Metastatic Pancreatic Cancer Market – Geographical Landscape

The market for advanced metastatic pancreatic cancer is segmented into regions such as North America, Latin America, Asia-Pacific Region, Europe, the Middle East & Africa. The largest region for the pancreatic market is North America, including the United States & Canada, which is a significant market for advanced metastatic pancreatic cancer treatments. The region benefits from advanced healthcare infrastructure, research institutions, and a high incidence of pancreatic cancer cases. The Asia-Pacific region, including countries like Japan, China, and India is witnessing a rising incidence of pancreatic cancer. Europe, particularly Western European countries, has a notable presence in the market. Access to healthcare and government-funded research initiatives contribute to advancements in pancreatic cancer treatment.

Global Advanced Metastatic Pancreatic Cancer Market – Key Development

  • On September 21, 2023, CARsgen Therapeutics Holdings Limited a company focused on innovative CAR-T cell therapies for the treatment of hematologic malignancies announced the treatment of metastatic pancreatic cancer with CARsgen’s CT041, an innovative Claudin publication.
  • On February 15, 2023, Purple Biotech dosed the first participant in the randomized stage of the phase II clinical trial of CM24 to treat advanced metastatic pancreatic cancer.
  • On September 21, 2022, the FDA approved Lilly’s Retevmo® (selpercatinib), the first and only RET inhibitor for adults with advanced or metastatic solid tumors with RET gene fusion.
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Research Methodology: Aspects

Market research is a crucial tool for organizations aiming to navigate the dynamic landscape of customer preferences, business trends, and competitive landscapes. At Cognizance Market Research, acknowledging the importance of robust research methodologies is vital to delivering actionable insights to our clientele. The significance of such methodologies lies in their capability to offer clarity in complexity, guiding strategic management with realistic evidence rather than speculation. Our clientele seek insights that excel superficial observations, reaching deep into the details of consumer behaviours, market dynamics, and evolving opportunities. These insights serve as the basis upon which businesses craft tailored approaches, optimize product offerings, and gain a competitive edge in an ever-growing marketplace.

The frequency of information updates is a cornerstone of our commitment to providing timely, relevant, and accurate insights. Cognizance Market Research adheres to a rigorous schedule of data collection, analysis, and distribution to ensure that our reports reflect the most current market realities. This proactive approach enables our clients to stay ahead of the curve, capitalize on emerging trends, and mitigate risks associated with outdated information.

Our research process is characterized by meticulous attention to detail and methodological rigor. It begins with a comprehensive understanding of client objectives, industry dynamics, and research scope. Leveraging a combination of primary and secondary research methodologies, we gather data from diverse sources including surveys, interviews, industry reports, and proprietary databases. Rigorous data analysis techniques are then employed to derive meaningful insights, identify patterns, and uncover actionable recommendations. Throughout the process, we remain vigilant in upholding the highest standards of data integrity, ensuring that our findings are robust, reliable, and actionable.

Key phases involved in in our research process are mentioned below:


Understanding Clients’ Objectives:

Extensive Discussions and Consultations:

  • We initiate in-depth discussions and consultations with our clients to gain a comprehensive understanding of their objectives. This involves actively listening to their needs, concerns, and aspirations regarding the research project.
  • Through these interactions, we aim to uncover the underlying motivations driving their research requirements and the specific outcomes they hope to achieve.

Industry and Market Segment Analysis:

  • We invest time and effort in comprehensively understanding our clients’ industry and market segment. This involves conducting thorough research into market trends, competitive dynamics, regulatory frameworks, and emerging opportunities or threats.
  • By acquiring a deep understanding of the broader industry landscape, we can provide context-rich insights that resonate with our clients’ strategic objectives.

Target Audience Understanding:

  • We analyze our clients’ target audience demographics, behaviors, preferences, and needs to align our research efforts with their consumer-centric objectives. This entails segmenting the audience based on various criteria such as age, gender, income level, geographic location, and psychographic factors.
  • By understanding the nuances of the target audience, we can tailor our research methodologies to gather relevant data that illuminates consumer perceptions, attitudes, and purchase intent.


Identifying Challenges and Opportunities:

  • We proactively identify the challenges and opportunities facing our clients within their respective industries. This involves conducting SWOT (Strengths, Weaknesses, Opportunities, Threats) analyses and competitive benchmarking exercises.
  • By identifying potential obstacles and growth drivers, we can provide strategic recommendations that help our clients navigate complexities and capitalize on emerging opportunities effectively.

Grasping Specific Goals:

  • We delve into the intricacies of our clients’ objectives to gain clarity on the specific goals they aim to accomplish through the research. This entails understanding their desired outcomes, such as market expansion, product development, or competitive analysis.
  • By gaining a nuanced understanding of our clients’ goals, we can tailor our research approach to address their unique challenges and opportunities effectively.

Data Collection:


Primary Research Process:

  • Surveys: We design and administer surveys tailored to capture specific information relevant to our clients’ objectives. This may involve employing various survey methodologies, such as online, telephone, or face-to-face interviews, to reach target audiences effectively.
  • Interviews: We conduct structured or semi-structured interviews with key stakeholders, industry experts, or target consumers to gather in-depth insights and perspectives on relevant topics. These interviews allow us to probe deeper into specific issues and uncover valuable qualitative data.
  • Focus Groups: We organize focus group discussions with carefully selected participants to facilitate interactive discussions and gather collective opinions, attitudes, and preferences. This qualitative research method provides rich contextual insights into consumer behaviors and perceptions.
  • Observations: We conduct observational research by directly observing consumer behaviors, interactions, and experiences in real-world settings. This method enables us to gather objective data on consumer actions and reactions without relying on self-reported information.

Secondary Research Process:

  • Literature Review: We conduct comprehensive literature reviews to identify existing studies, academic articles, and industry reports relevant to the research topic. This helps us gain insights into previous research findings, theoretical frameworks, and best practices.
  • Industry Reports: We analyze industry reports published by reputable trade associations (whitepapers, research studies, etc.), and government agencies (U.S. Census Bureau, Bureau of Labor Statistics, and Securities and Exchange Commission etc.) to obtain macro-level insights into market trends, competitive landscapes, and industry dynamics.
  • Government Publications: We review government publications, such as economic reports, regulatory documents, and statistical databases, to gather relevant data on demographics, market size, consumer spending patterns, and regulatory frameworks.
  • Online Databases: We leverage online databases, such as industry portals, and academic repositories (PubMed Central (PMC), ScienceDirect, SSRN (Social Science Research Network), Directory of Open Access Journals (DOAJ), NCBI, etc.), to access a wide range of secondary data sources, including market statistics, financial data, and industry analyses.



Data Analysis:

The data analysis phase serves as a critical juncture where raw data is transformed into actionable insights that inform strategic decision-making. Through the utilization of analytical methods such as statistical analysis and qualitative techniques like thematic coding, we uncover patterns, correlations, and trends within the data. By ensuring the integrity and validity of our findings, we strive to provide clients with accurate and reliable insights that accurately reflect the realities of the market landscape.


Transformation of Raw Data:

  • Upon collecting the necessary data, we transition into the data analysis phase, where raw data is processed and transformed into actionable insights. This involves organizing, cleaning, and structuring the data to prepare it for analysis.

Utilization of Analytical Methods:

  • Depending on the research objectives, we employ a diverse range of analytical methods to extract meaningful insights from the data. These methods include statistical analysis, trend analysis, regression analysis, and qualitative coding.

Statistical Analysis:

  • Statistical tools are instrumental in uncovering patterns, correlations, and trends within the data. By applying statistical techniques such as descriptive statistics, hypothesis testing, and multivariate analysis, we can discern relationships and derive valuable insights.

Qualitative Analysis Techniques:

  • In addition to quantitative analysis, we leverage qualitative analysis techniques to gain deeper insights from qualitative data sources such as interviews or open-ended survey responses. One such technique is thematic coding, which involves systematically categorizing and interpreting themes or patterns within qualitative data.

Integrity and Validity Maintenance:

  • Throughout the analysis process, we maintain a steadfast commitment to upholding the integrity and validity of our findings. This entails rigorous adherence to established methodologies, transparency in data handling, and thorough validation of analytical outcomes.

Data Validation:

The final phase of our research methodology is data validation, which is essential for ensuring the reliability and credibility of our findings. Validation involves scrutinizing the collected data to identify any inconsistencies, errors, or biases that may have crept in during the research process. We employ various validation techniques, including cross-referencing data from multiple sources, conducting validity checks on survey instruments, and seeking feedback from independent experts or peer reviewers. Additionally, we leverage internal quality assurance protocols to verify the accuracy and integrity of our analysis. By subjecting our findings to rigorous validation procedures, we instill confidence in our clients that the insights they receive are robust, reliable, and trustworthy.


Importance of Data Validation:

  • Data validation is the final phase of the research methodology, crucial for ensuring the reliability and credibility of the findings. It involves a systematic process of reviewing and verifying the collected data to detect any inconsistencies, errors, or biases.

Scrutiny of Collected Data:

  • The validation process begins with a thorough scrutiny of the collected data to identify any discrepancies or anomalies. This entails comparing data points, checking for outliers, and verifying the accuracy of data entries against the original sources.

Validation Techniques:

  • Various validation techniques are employed to ensure the accuracy and integrity of the data. These include cross-referencing data from multiple sources to corroborate findings, conducting validity checks on survey instruments to assess the reliability of responses, and seeking feedback from independent experts or peer reviewers to validate the interpretation of results.

Internal Quality Assurance Protocols:

  • In addition to external validation measures, internal quality assurance protocols are implemented to further validate the accuracy of the analysis. This may involve conducting internal audits, peer reviews, or data validation checks to ensure that the research process adheres to established standards and guidelines.
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