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Global Hyperpigmentation Disorder Treatment Market “(By Treatment Type: Pharmacological: (Synthetic origin): Hydroquinone, Azelaic Acid, Vitamin C & Topical Corticosteroids. (Natural origin): Kojik acid, Citrus extracts, and Licorice Extracts. (Non -Pharmacological: Laser treatments, Chemical peels, Phototherapy & Microdermabrasion), (By End-user: Hospitals, Esthetic Clinics& Dermatology Centers & Others) (By Disease Indication: Melasma, Post-inflammatory Hyperpigmentation, Solar Lentigines & Others), (By region: North America, Europe, Asia Pacific, Latin America, and Middle East & Africa)” – segmentation, Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2022-2030

A prominent research firm, Cognizance Market Research added a cutting-edge industry report on the “Global Hyperpigmentation Disorder Treatment Market.” The report studies the current as well as past growth trends and opportunities for the market to gain valuable insights during the forecast period from 2022 to 2030.

Global Hyperpigmentation Disorder Treatment Market Analysis

According to cognizance market research, the global hyperpigmentation disorder treatment market was valued at US$ 4,238.4 Million in 2022 and is anticipated to reach US$ 8,171.2 Million by the end of 2030 with a CAGR of 8.6% from 2023 to 2030.

hyperpigmentation disorder treatment market

What is the global hyperpigmentation disorder treatment market?

 Hyperpigmentation is a widespread, typically unharmful disorder where some areas of the skin are darker than that of the skin surrounding. It happens when specific skin cells produce an excessive amount of melanin pigment. Freckles, age spots, or significantly darker patches of skin can all be signs of hyperpigmentation. Injuries or inflammation of the skin, UV damage, unnatural skin growths, hormone imbalances, maternity, or other medical disorders can all lead to hyperpigmentation. Hyperpigmentation can also be brought on by various medications, particularly some anticancer medications.

For the treatment of hyperpigmentation, numerous therapies, either alone or in combination with two or more other therapies, have been investigated. The most prevalent conditions are by far melasma and vitiligo. Additional factors that contribute to melasma development include estrogen levels, genetic susceptibility, and phototoxic medication. The majority of the disorders are aesthetically upsetting even if they seem to be harmless. Pigmentation diseases are treated with major treatment types like using, topical medicines, chemical peels, light or laser therapy, cryotherapy, or a combination of these approaches to address the underlying issue. Many histological and immunohistochemical investigations have enriched the picture of the hyperpigmentation disorders therapy market by improving researchers’ understanding of the etiology of melasma. Topical hydroquinone (HQ), topical retinoic acid (RA), topical corticosteroid (triple combination), and topical glycolic acid (GA) (double combination) are a few of the most important therapeutic options.

Throughout the projection period, it is predicted that the market for hyperpigmentation disorder therapy will gain importance due to rising R&D expenditure on cutting-edge technologies and a drop in the stigma attached to pigmentation in society. Additionally, it is projected that increased awareness of skin rejuvenation and possible treatments as well as the rising prevalence of disorders connected to hyperpigmentation would encourage market growth on a global scale.

Global Hyperpigmentation Disorder Treatment Market Outlook

Companies that specialize in the treatment of hyperpigmentation issues have intriguing potential because of cosmeceutical technology breakthroughs and the increased value of using cosmeceuticals in skincare. Large corporations are spending more and more on nanotechnology to develop novel goods, expand their market share, and increase sales.

By increasing the loading capability, solubility, stability, skin permeability, and safety of active ingredients, nanotechnology significantly helps to promote the creation of cosmeceutical formulations. The use of topical hydroquinone, which has less systemic absorption and adequate skin penetration as well as fewer side effects, is an appealing method for treating hyperpigmentation.

The need for post-inflammatory hyperpigmentation (PIH) therapies caused by the prevalence of persons with darker skin tones is boosting the marketplace for the treatment of hyperpigmentation illnesses.

Despite an extensive body of research on the pathophysiology of PIH, there is still a necessity in the world market for the treatment of hyperpigmentation disorders. Several compounds, including dexamethasone, tretinoin, and hydroquinone, are being researched to close this gap.

Because of the COVID-19 pandemic, the market for treating pigmentation disorders has indeed been impacted. 1,360 dermatologists in the UK were found to be assessing the consequences of the epidemic, according to a report by Hamilton Fraser Cosmetic Insurance. The poll found that 99.78% of respondents and their professions were affected by the epidemic.

With the rise in launches and R&D activities by top corporations, the industry is expanding. For instance, Incyte Corporation was conducting a phase II US clinical trial for the medication Ruxolitinib to treat vitiligo, as reported by the National Clinical Trials (NCT) Registry. The market will grow if the drug Ruxolitinib is soon approved for the treatment of Vitiligo.

Segment Analysis:

The study offers a thorough review of the worldwide market for treating hyperpigmentation disorders by therapy type (topical treatment), end-user, illness indication, and geography.

Based on the type of treatment, there are two types of treatment available there, pharmacological therapy & non -pharmacological therapy.  The pharmacological segment is further divided into synthetic origin & natural origin. The synthetic segment consists of hydroquinone azelaic acid, vitamin C, & topical corticosteroids. Whereas the natural segment consists of Kojik acid, citrus extracts & licorice extract. A considerable percentage of the market is expected to be occupied by topical drugs.

 The non -non-pharmacological segment consists of laser treatments, chemical peels, phototherapy, and microdermabrasion. Patients with hyperpigmentation problems see dermatologists more often, and topical medications are frequently given to these patients. As a result of better clinical results for individuals with pigmentation problems, the topical therapy category presently holds a monopoly on the global market. The most common topical medications worldwide are hydroquinone, L-ascorbic acid, azelaic acid, etc.

Based on end users, the hyperpigmentation disorders treatment statistics comprise hospitals, aesthetic clinics, dermatological centers, and others. The hospital sector accounted for most of the market revenue for the treatment of hyperpigmentation disorders in 2022, and it is anticipated to increase at the fastest rate from 2022 to 2030. A surge in dermatological and aesthetic clinics is what is driving this market. The other group, however, is also anticipated to grow during the prediction period. Producers and distributors of cosmeceuticals for hyperpigmentation are improving their supply chains to satisfy the increasing need for treatments for hyperpigmentation diseases.

Melasma, post-inflammatory hyperpigmentation & solar lentigines are part of the Hyperpigmentation Disorders Therapy Market segmentation based on disease indication. In 2022, the market for treating hyperpigmentation disorders was dominated by the melasma category, and during the forecast period of 2022–2030, it is anticipated to develop at the fastest rate. Because of its high occurrence in white people, who make up between 55% and 60% of the world’s population, melasma presently leads the ailment category. 90% of women worldwide experience melasma, which is accompanied by hormonal changes, pregnancy, and the use of reproductive control.

Geographical Analysis

Based on geography the market for global hyperpigmentation disorders treatment has been categorized into North America, Europe, Asia Pacific, Latin America, and Middle East and Africa. North America, Europe, and the Asia-Pacific region were the most preferred regions for hyperpigmentation problem treatment. Asia Pacific will continue to dominate the worldwide market for treatments for hyperpigmentation disorders over the projected period because of factors such as rising self-consciousness about one’s appearance, increased usage of minimally invasive procedures, and a highly developed healthcare system.

As reported in a 2022 article from the National Centre for Biotechnology Information, US National Library of Medicine, albinism is more common in the American region, with rates of 1:10,000 among African Americans and 1:36,000 overall. Therefore, it is projected that as albinism grows more common in the country, the market for treating hyperpigmentation problems will expand.

Yet the region with the highest CAGR is Asia Pacific, where growth is being led by China, India, and Japan. Due to reasons such as the increasing interest of key players in developing Asian countries, penetration, and adoption of cutting-edge technology, rising disposable incomes, and expanding government assistance, the market for treatments for hyperpigmentation disorders is growing in this region.

An increase in the use of laser therapy for a variety of skin issues, as well as a decline in societal stigmas and an increase in the adoption of treatment options for pigmentation disorders, are projected to propel the regional market.

geographical analysis

The report offers the revenue of the global hyperpigmentation disorder treatment market for the period 2020-2030, considering 2020 & 2021 as historical years, 2022 as the base year, and 2023 to 2030 as the forecast year. The report also provides the compound annual growth rate (CAGR) for the global hyperpigmentation disorder treatment market for the forecast period. The global hyperpigmentation disorder treatment market report provides insights and in-depth analysis into developments impacting enterprises and businesses on a regional and global level. The report covers the global hyperpigmentation disorder treatment market performance in terms of revenue contribution from several segments and comprises a detailed analysis of key drivers, trends, restraints, and opportunities prompting revenue growth of the global hyperpigmentation disorder treatment market.

The report has been prepared after wide-ranging secondary and primary research. Secondary research included internet sources, numerical data from government organizations, trade associations, and websites. Analysts have also employed an amalgamation of bottom-up and top-down approaches to study numerous phenomena in the global hyperpigmentation disorder treatment market. Secondary research involved a detailed analysis of significant players’ product portfolios. Literature reviews, press releases, annual reports, white papers, and relevant documents have also been studied to understand the global hyperpigmentation disorder treatment market. Primary research involved a great extent of research efforts, wherein experts carried out interviews telephonic as well as questioner-based with industry experts and opinion-makers.

The report includes an executive summary, along with a growth pattern of different segments included in the scope of the study. The Y-o-Y analysis with elaborate market insights has been provided in the report to comprehend the Y-o-Y trends in the global hyperpigmentation disorder treatment market. Additionally, the report focuses on altering competitive dynamics in the global hyperpigmentation disorder treatment market. These indices serve as valued tools for present market players as well as for companies interested in participating in the global hyperpigmentation disorder treatment market. The subsequent section of the hyperpigmentation disorder treatment reports highlights the USPs, which include key industry events (product launch, research partnership, acquisition, etc.), technology advancements, pipeline analysis, prevalence data, and regulatory scenarios.

Global Hyperpigmentation Disorder Treatment Market Competitive Landscape

The “Global Hyperpigmentation Disorder Treatment Market” study report will provide valuable insight with an emphasis on the global market including some of the major players such as,

  • Bayer AG
  • RXi Pharmaceuticals
  • Galderma laboratories
  • SkinCeuticals International
  • EpiPharm AG
  •  Obagi Cosmeceuticals LLC.
  • Candela Corporation
  •  L’Oréal S.A.
  • Aerolase Corporation
  • Lumenis Be Ltd
  • Other Prominent Players

The report explores the competitive scenario of the hyperpigmentation disorder treatment market. Major players operating in the hyperpigmentation disorder treatment market have been identified and profiled for unique commercial attributes. Company overview (company description, product portfolio, geographic presence, employee strength, Key management, etc.), financials, SWOT analysis, recent developments, and key strategies are some of the features of companies profiled in the hyperpigmentation disorder treatment market report.


Global Hyperpigmentation Disorder Treatment Market, by Treatment Type

Pharmacological therapy

Synthetic Origin

  • Hydroquinone
  • Azelaic acid
  • Vitamin C
  • Topical Corticosteroids

Natural Origin

  • Kojik acid
  • Citrus extracts
  • Licorice extracts

Non -Pharmacological therapy

  • Laser treatments
  • Chemical peels
  • Phototherapy
  • Microdermabrasion

Global Hyperpigmentation Disorder Treatment Market, by End-user

  • Hospitals
  • Esthetic clinics & dermatology centers
  • others

Global Hyperpigmentation Disorder Treatment Market, by Disease Indication

  • Melasma
  • Post-inflammatory hyperpigmentation
  • Solar lentigines
  • others

Global Hyperpigmentation Disorder Treatment Market, by region

North America

  • The U.S.
  • Canada


  • Germany
  • The U.K.
  • France
  • Spain
  • Italy
  • Rest of Europe

Asia Pacific

  • Japan
  • China
  • India
  • Australia & New Zealand
  • South Korea
  • Rest of Asia Pacific

Latin America

  • Brazil
  • Mexico
  • Rest of Latin America

Middle East & Africa

  • GCC
  • South Africa
  • Rest of the Middle East & Africa
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Table of Content

Research Methodology: Aspects

Market research is a crucial tool for organizations aiming to navigate the dynamic landscape of customer preferences, business trends, and competitive landscapes. At Cognizance Market Research, acknowledging the importance of robust research methodologies is vital to delivering actionable insights to our clientele. The significance of such methodologies lies in their capability to offer clarity in complexity, guiding strategic management with realistic evidence rather than speculation. Our clientele seek insights that excel superficial observations, reaching deep into the details of consumer behaviours, market dynamics, and evolving opportunities. These insights serve as the basis upon which businesses craft tailored approaches, optimize product offerings, and gain a competitive edge in an ever-growing marketplace.

The frequency of information updates is a cornerstone of our commitment to providing timely, relevant, and accurate insights. Cognizance Market Research adheres to a rigorous schedule of data collection, analysis, and distribution to ensure that our reports reflect the most current market realities. This proactive approach enables our clients to stay ahead of the curve, capitalize on emerging trends, and mitigate risks associated with outdated information.

Our research process is characterized by meticulous attention to detail and methodological rigor. It begins with a comprehensive understanding of client objectives, industry dynamics, and research scope. Leveraging a combination of primary and secondary research methodologies, we gather data from diverse sources including surveys, interviews, industry reports, and proprietary databases. Rigorous data analysis techniques are then employed to derive meaningful insights, identify patterns, and uncover actionable recommendations. Throughout the process, we remain vigilant in upholding the highest standards of data integrity, ensuring that our findings are robust, reliable, and actionable.

Key phases involved in in our research process are mentioned below:


Understanding Clients’ Objectives:

Extensive Discussions and Consultations:

  • We initiate in-depth discussions and consultations with our clients to gain a comprehensive understanding of their objectives. This involves actively listening to their needs, concerns, and aspirations regarding the research project.
  • Through these interactions, we aim to uncover the underlying motivations driving their research requirements and the specific outcomes they hope to achieve.

Industry and Market Segment Analysis:

  • We invest time and effort in comprehensively understanding our clients’ industry and market segment. This involves conducting thorough research into market trends, competitive dynamics, regulatory frameworks, and emerging opportunities or threats.
  • By acquiring a deep understanding of the broader industry landscape, we can provide context-rich insights that resonate with our clients’ strategic objectives.

Target Audience Understanding:

  • We analyze our clients’ target audience demographics, behaviors, preferences, and needs to align our research efforts with their consumer-centric objectives. This entails segmenting the audience based on various criteria such as age, gender, income level, geographic location, and psychographic factors.
  • By understanding the nuances of the target audience, we can tailor our research methodologies to gather relevant data that illuminates consumer perceptions, attitudes, and purchase intent.


Identifying Challenges and Opportunities:

  • We proactively identify the challenges and opportunities facing our clients within their respective industries. This involves conducting SWOT (Strengths, Weaknesses, Opportunities, Threats) analyses and competitive benchmarking exercises.
  • By identifying potential obstacles and growth drivers, we can provide strategic recommendations that help our clients navigate complexities and capitalize on emerging opportunities effectively.

Grasping Specific Goals:

  • We delve into the intricacies of our clients’ objectives to gain clarity on the specific goals they aim to accomplish through the research. This entails understanding their desired outcomes, such as market expansion, product development, or competitive analysis.
  • By gaining a nuanced understanding of our clients’ goals, we can tailor our research approach to address their unique challenges and opportunities effectively.

Data Collection:


Primary Research Process:

  • Surveys: We design and administer surveys tailored to capture specific information relevant to our clients’ objectives. This may involve employing various survey methodologies, such as online, telephone, or face-to-face interviews, to reach target audiences effectively.
  • Interviews: We conduct structured or semi-structured interviews with key stakeholders, industry experts, or target consumers to gather in-depth insights and perspectives on relevant topics. These interviews allow us to probe deeper into specific issues and uncover valuable qualitative data.
  • Focus Groups: We organize focus group discussions with carefully selected participants to facilitate interactive discussions and gather collective opinions, attitudes, and preferences. This qualitative research method provides rich contextual insights into consumer behaviors and perceptions.
  • Observations: We conduct observational research by directly observing consumer behaviors, interactions, and experiences in real-world settings. This method enables us to gather objective data on consumer actions and reactions without relying on self-reported information.

Secondary Research Process:

  • Literature Review: We conduct comprehensive literature reviews to identify existing studies, academic articles, and industry reports relevant to the research topic. This helps us gain insights into previous research findings, theoretical frameworks, and best practices.
  • Industry Reports: We analyze industry reports published by reputable trade associations (whitepapers, research studies, etc.), and government agencies (U.S. Census Bureau, Bureau of Labor Statistics, and Securities and Exchange Commission etc.) to obtain macro-level insights into market trends, competitive landscapes, and industry dynamics.
  • Government Publications: We review government publications, such as economic reports, regulatory documents, and statistical databases, to gather relevant data on demographics, market size, consumer spending patterns, and regulatory frameworks.
  • Online Databases: We leverage online databases, such as industry portals, and academic repositories (PubMed Central (PMC), ScienceDirect, SSRN (Social Science Research Network), Directory of Open Access Journals (DOAJ), NCBI, etc.), to access a wide range of secondary data sources, including market statistics, financial data, and industry analyses.





Data Analysis:

The data analysis phase serves as a critical juncture where raw data is transformed into actionable insights that inform strategic decision-making. Through the utilization of analytical methods such as statistical analysis and qualitative techniques like thematic coding, we uncover patterns, correlations, and trends within the data. By ensuring the integrity and validity of our findings, we strive to provide clients with accurate and reliable insights that accurately reflect the realities of the market landscape.



Transformation of Raw Data:

  • Upon collecting the necessary data, we transition into the data analysis phase, where raw data is processed and transformed into actionable insights. This involves organizing, cleaning, and structuring the data to prepare it for analysis.

Utilization of Analytical Methods:

  • Depending on the research objectives, we employ a diverse range of analytical methods to extract meaningful insights from the data. These methods include statistical analysis, trend analysis, regression analysis, and qualitative coding.

Statistical Analysis:

  • Statistical tools are instrumental in uncovering patterns, correlations, and trends within the data. By applying statistical techniques such as descriptive statistics, hypothesis testing, and multivariate analysis, we can discern relationships and derive valuable insights.

Qualitative Analysis Techniques:

  • In addition to quantitative analysis, we leverage qualitative analysis techniques to gain deeper insights from qualitative data sources such as interviews or open-ended survey responses. One such technique is thematic coding, which involves systematically categorizing and interpreting themes or patterns within qualitative data.

Integrity and Validity Maintenance:

  • Throughout the analysis process, we maintain a steadfast commitment to upholding the integrity and validity of our findings. This entails rigorous adherence to established methodologies, transparency in data handling, and thorough validation of analytical outcomes.

Data Validation:

The final phase of our research methodology is data validation, which is essential for ensuring the reliability and credibility of our findings. Validation involves scrutinizing the collected data to identify any inconsistencies, errors, or biases that may have crept in during the research process. We employ various validation techniques, including cross-referencing data from multiple sources, conducting validity checks on survey instruments, and seeking feedback from independent experts or peer reviewers. Additionally, we leverage internal quality assurance protocols to verify the accuracy and integrity of our analysis. By subjecting our findings to rigorous validation procedures, we instill confidence in our clients that the insights they receive are robust, reliable, and trustworthy.


Importance of Data Validation:

  • Data validation is the final phase of the research methodology, crucial for ensuring the reliability and credibility of the findings. It involves a systematic process of reviewing and verifying the collected data to detect any inconsistencies, errors, or biases.

Scrutiny of Collected Data:

  • The validation process begins with a thorough scrutiny of the collected data to identify any discrepancies or anomalies. This entails comparing data points, checking for outliers, and verifying the accuracy of data entries against the original sources.

Validation Techniques:

  • Various validation techniques are employed to ensure the accuracy and integrity of the data. These include cross-referencing data from multiple sources to corroborate findings, conducting validity checks on survey instruments to assess the reliability of responses, and seeking feedback from independent experts or peer reviewers to validate the interpretation of results.

Internal Quality Assurance Protocols:

  • In addition to external validation measures, internal quality assurance protocols are implemented to further validate the accuracy of the analysis. This may involve conducting internal audits, peer reviews, or data validation checks to ensure that the research process adheres to established standards and guidelines.

Report Scope:



Market Size

US$ 8,171.2 Million (2030)

Compound Annual Growth Rate (CAGR)


Base Year


Forecast Period


Forecast Units

Value (US$ Million)

Report Coverage

Revenue Forecast, Competitive Landscape, Growth Factors, and Trends

Geographies Covered

North America, Europe, Asia Pacific, Latin America, Middle East & Africa

Countries Covered

U.S., Canada, Germany, U.K., France, Spain, Italy, Rest of Europe, Japan, China, India, Australia & New Zealand, South Korea, Rest of Asia Pacific, Brazil, Mexico, Rest of Latin America, GCC, South Africa, Rest of Middle East & Africa

Key Companies Profiled

Bayer AG, RXi Pharmaceuticals, ALLERGAN, Galderma laboratories, SkinCeuticals International, PIERRE FABRE GROUP, etc.

Key Questions Answered in Hyperpigmentation Disorder Treatment Market Report

Bayer AG, RXi Pharmaceuticals, ALLERGAN, Galderma laboratories, SkinCeuticals International, PIERRE FABRE GROUP, etc.

Trend: Increased public awareness and disease diagnosis. Drivers: technological advancement, adoption of minimally invasive procedures, increasing medical tourism for aesthetics, etc., Opportunities: problems associated with pigmentation, expanding R&D for clinical trials and drug development, Challenges: high cost and complications & risks associated with aesthetic products and treatment.

North America

Topical treatment (cosmeceuticals)

Strategic acquisition, research & development activities, and product launches.

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