Agitation in Delirium Market

Agitation in Delirium Market - Global Industry, Analysis, Size, Share, Growth, Trends, and Forecasts 2023-2030

Delirium is a mental state in which you are confused, disoriented, and not able to think or remember clearly. It usually starts suddenly. It is often temporary and treatable. Excited delirium also known as agitated delirium or hyperactive delirium syndrome with severe agitation is a controversial and pseudoscientific diagnosis characterized as a potentially fatal state of extreme agitation and delirium. It has typically been diagnosed postmortem in young adult males, disproportionately black men, who were physically restrained at the time of death most often by law enforcement personnel. The symptoms of agitated delirium include aggressive behavior, extreme physical strength, and hyperthermia. The term agitated delirium is sometimes used interchangeably with acute behavioral disturbance. People diagnosed with agitated delirium are frequently claimed to have acute drug intoxication generally involving phencyclidine and cocaine. These may include positional asphyxia, hyperthermia, drug toxicity, and catecholamine-induced fatal abnormal heart rhythms.  The medical professional does not know the exact cause of delirium. The causes of agitation in delirium are multifaceted and can be attributed to the underlying medical conditions and factors triggering the delirium. Common causes include infections, medication side effects, metabolic imbalance, and withdrawal from substances. Agitation may also result from the person’s inability to understand their surroundings and the unfamiliar hospital or clinical environment, leading to heightened anxiety and frustration.

In some cases when pharmacological approaches are insufficient, healthcare providers may use medications to manage severe agitation, but this should be done with caution due to potential side effects. Continue research into effective management and prevention strategies as well as a greater emphasis on personalized approaches to address unique needs of each patient.

Global Agitation in Delirium Market – Competitive Landscape

On August 21, 2023, PIPRA met the venture leader Medtech focusing on an innovative AI-based pre-operative tool to assess the risk of patients developing post-operative delirium. The global agitation in the delirium market continues to evolve, competition is likely to intensify with a focus on personalized and precise approaches for managing agitation.

Some of the Key Players in the Global Agitation in the Delirium Market Include –

  • Johnson & Johnson
  • Teva Pharmaceutical Industries Ltd.
  • Amneal Pharmaceutical LLC.
  • Lundbeck A/S
  • Eli Lily
  • Pfizer
  • GlaxoSmithKline
  • Otsuka Holdings Co. Ltd.
  • Fraser Healthcare

Global Agitation in Delirium Market – Growth Drivers

The global aging population is expanding, leading to a higher prevalence of delirium among the elderly, driving the need for better delirium management and care due to this the market for agitation in delirium increases. According to the National Center for Biotechnology Information (NCBI), delirium characteristics were observed in 0.6% of patients (260/43,838) representing 13% of agitated patients (114/866) without delirium symptoms and 26% (68/260) with delirium symptoms. without delirium symptoms Improvements in healthcare facilities, infrastructure, and awareness have enhanced delirium diagnosis and treatment rates increasing the market’s potential. Continuous research into delirium causes and risk factors has spurred innovation in pharmaceuticals and non-pharmaceutical interventions, offering new treatment options. Regulatory bodies worldwide are emphasizing the importance of delirium prevention and management, creating market opportunities for pharmaceutical and medical device companies. Technology-driven solutions, such as digital assessment tools and telemedicine platforms, are being utilized to monitor and manage delirium, improving patient care. Collaboration between pharmaceutical companies, research institutions, and healthcare providers is fostering the development of more effective delirium management strategies.

Global Agitation in Delirium Market – Restraints

Delirium can often go undiagnosed or be misdiagnosed as other conditions due to its fluctuating nature and complex presentation, leading to delayed or inappropriate treatment. The high healthcare cost of delirium is also a burden on healthcare systems. According to the National Center for Biotechnology Information (NCBI), total costs attributable to delirium ranged from USD 16,303 to USD 64,421 per patient, implying the national burden of delirium on the health care system ranges from USD 38 billion to USD 152 billion each year. There is a lack of awareness among healthcare professionals and the general public about delirium, its risk factors, and its consequences, which can hinder early recognition and intervention. Pharmacological interventions are available for managing agitation in delirium, but they come with potential side effects and risks, so deciding to use them is a complex one. Implementing non-pharmacological interventions and new technologies for delirium management may face resistance in traditional healthcare practices. Adequate delirium management often requires additional healthcare resources, including trained personnel and specialized tools. Limited sources may struggle to provide optimal care. Delirium has multiple underlying causes, which makes it a heterogenous condition. Identifying the specific cause and tailoring treatment can be challenging.

Global Agitation in Delirium Market – Opportunities

There was a significant opportunity to raise awareness about delirium among healthcare professionals, caregivers, and the public. Education and training programs can help improve early detection and intervention. The development of novel non-pharmacological interventions, such as behavioral therapies, sensory approaches, and environmental modifications offers the potential to improve agitation management in delirium without the risk associated with medication. Continued research into the underlying causes of delirium and the development of new diagnostic tools and treatment options can drive global agitation in delirium market growth and improved patient outcomes.

Global Agitation in Delirium Market – Geographical Insight

The global market for agitation in delirium is segmented into regions such as North America, Latin America, Asia-Pacific, Europe, the Middle East & Asia. North America is the largest market for global agitation in delirium due to growing emphasis on the importance of delirium management, with healthcare institutions implementing guidelines and educational programs. Asia-Pacific is the growing region for global agitation in the delirium market with countries such as Japan & South Korea there is growing recognition of delirium especially in the context of their aging populations.  European countries with aging populations, such as the United Kingdom, Germany, and Italy are actively addressing delirium through research and healthcare initiatives.

Global Agitation in Delirium Market – Key Development

  • On June 8, 2023, a UI researcher developed an algorithm to spot the risk of delirium in patients.
  • On January 31, 2023, Teva Pharmaceutical has opened expansion into long-acting injectables, kicking off phase 3 trials of a prospect based on the same technology as its near-approval schizophrenia drug.
  • On December 13, 2021, Masimo-derived Masimo SedLine® Brain function monitoring aids early identification of patients at risk of developing postoperative delirium.
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Agitation in Delirium Market


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